The principal aim of this line is the experimental study of the mechanical and microstructural behaviour of materials focusing on biomaterials and biological tissue. The analysis of the composition, morphology, microstructure and macroscopic behaviour allow to develop advance constitutive law able to reproduce the main physical features of the materials and afterward will be used in the rest of research lines of the group. The principal experimental tests and analysis are uniaxial, biaxial, compressive, shear stress, indentation, inflation, tomography, histology, in order to capture phenomena such as elastic, viscoelastic, fatigue or softening behaviours. Histological and microstructural tests permit to extract important information to model and simulate the response of the tissue at microstructural or cellular level.
Concerning the cardiovascular research line, the AMB group has a wide experience in the development of constitutive laws for vascular tissue and also experimental characterization of mechanical behaviour of blood vessels.
Currently our research lines are focused on simulating multiphysics and multiscale phenomena. We have developed advanced constitutive laws to reproduce inelastic effects on soft tissue that incorporates microstructural information, which determine the macroscopic performance of the tissue.
The experimental tests performed in our tissue characterization laboratory allow fitting and validating the developed models. Interactions of the tissue with biomaterials or medical devices have been also studied. We have important collaboration with clinical partners in hospitals to apply our research in problems with special clinical interest.